RESISTOR: an algorithm for predicting resistance mutations using Pareto optimization over multistate protein design and mutational signatures^†

Link to Software and the Supplementary Information


J Comput Biol. June 2022. [Epub ahead of print]

Nathan Guerin
Department of Computer Science, Duke University,
Durham, NC 27708, USA

Teresa Kaserer
Institute of Pharmacy/Pharmaceutical Chemistry, University of Innsbruck,
Innsbruck, Austria

Bruce R. Donald^*
Department of Computer Science, Duke University,
Department of Biochemistry, Duke University Medical Center,
Department of Chemistry, Duke University,
Department of Mathematics, Duke University,
Durham, NC 27708, USA


^*Corresponding author
^†This work is supported by grants R01-GM078031, R01GM118543, and R35-GM144042 from the National Institutes of Health to B.R.D. and P34376 from the Austrian Science Fund to T.K.